- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Mammaglobin Antibody Mouse Monoclonal MGB/2704 / Mammaglobin A Antibody [clone MGB/2704] (V8491)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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V8491-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
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V8491-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
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V8491SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
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| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | MGB/2704 |
| Purity | Protein G affinity chromatography |
| UniProt | Q13296 |
| Localization | Cytoplasm |
| Applications | Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT |
| Limitations | This Mammaglobin antibody is available for research use only. |
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Mammaglobin A (SCGB2A2) is a secreted epithelial glycoprotein encoded by the SCGB2A2 gene and belongs to the secretoglobin family of small secreted proteins associated with mammary epithelial differentiation. Mammaglobin Antibody Mouse Monoclonal MGB/2704 recognizes Mammaglobin A / SCGB2A2 and targets a protein widely studied as a marker of mammary epithelial cells and breast carcinoma.
Mammaglobin antibody, also referred to as Mammaglobin A antibody or SCGB2A2 antibody in the literature, detects a protein predominantly produced by luminal epithelial cells of the mammary gland. Mammaglobin A is secreted into glandular lumens as part of normal epithelial secretory activity within mammary tissue. Because of this relatively restricted tissue distribution, Mammaglobin expression has been extensively examined in studies of mammary gland biology and breast tumor origin.
Structurally, Mammaglobin A contains conserved cysteine residues characteristic of secretoglobin family proteins that contribute to stable folding within epithelial secretory pathways. As a secreted epithelial protein, Mammaglobin is typically detected within the cytoplasm of mammary epithelial cells and may also be present within glandular luminal secretions depending on tissue architecture and experimental preparation. These localization features reflect the protein's role in epithelial secretory processes and glandular differentiation.
Expression of Mammaglobin A is frequently observed in breast epithelial cells and breast carcinoma specimens, where it reflects the differentiated state of mammary epithelial tumor cells. In breast tumors, Mammaglobin expression is often detected in epithelial tumor cell populations forming glandular structures, while surrounding stromal cells and non-epithelial tissue elements generally show little to no staining. These expression patterns have made Mammaglobin a valuable protein marker in breast cancer research and epithelial tumor characterization.
Mammaglobin Antibody Mouse Monoclonal (clone MGB/2704) is developed to detect Mammaglobin A / SCGB2A2 in protein expression studies involving mammary epithelial tissues and breast cancer models. Antibodies targeting Mammaglobin are widely used to investigate epithelial differentiation, tumor cell identity, and Mammaglobin expression patterns in mammary gland biology and breast tumor research.
Optimal dilution of the Mammaglobin Antibody Mouse Monoclonal MGB/2704 should be determined by the researcher.
Recombinant full-length human Mammaglobin-1 protein was used as the immunogen for the Mammaglobin antibody.
Store the Mammaglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Mammaglobin A antibody, SCGB2A2 antibody, Mammaglobin breast marker antibody, Secretoglobin family 2A member 2 antibody, Mammary gland secretoglobin antibody
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