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Home >> Antibodies >> Mammaglobin Antibody / SCGB2A2

Mammaglobin Antibody / SCGB2A2 [clone MGB/4056] (V8616)

  Catalog No Formulation Size Price (USD)  
Image V8616-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8616-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8616SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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HC staining of FFPE human breast carcinoma with Mammaglobin antibody (clone MGB/4056). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
HC staining of FFPE human breast carcinoma with Mammaglobin antibody (clone MGB/4056). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Mammaglobin antibody (clone MGB/4056). These results demonstrate the foremost specificity of the MGB/4056 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name MGB/4056
Purity Protein G affinity chromatography
UniProt Q13296
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This Mammaglobin antibody is available for research use only.
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Description

Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Application Notes

Optimal dilution of the Mammaglobin antibody should be determined by the researcher.

Immunogen

Recombinant full-length human Mammaglobin-1 protein was used as the immunogen for the Mammaglobin antibody.

Storage

Store the Mammaglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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