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Home >> Antibodies >> LXN Antibody / Latexin

LXN Antibody / Latexin (F54377)

  Catalog No Formulation Size Price (USD)  
Image F54377-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54377-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC testing of FFPE human spleen tissue with LXN antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
IHC testing of FFPE human prostate carcinoma tissue with LXN antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of human MCF7 cell lysate with LXN antibody. Predicted molecular weight ~26 kDa.
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with LXN antibody.
Flow cytometry testing of human WiDr cells with LXN antibody; Blue=isotype control, Green= LXN antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt Q9BS40
Localization Cytoplasmic
Applications Immunohistochemistry (FFPE) : 1:25
Flow cytometry : 1:25 (1x10e6 cells)
Western blot : 1:500-1:2000
Limitations This LXN antibody is available for research use only.
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Description

Latexin possesses nearly irreversible, non-competitive and potent inhibition of zinc-dependent metallocarboxypeptidases CPA1, CPA2, and CPA4. It is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Latexin plays a role in regional specification and/or morphogenesis of the forebrain.

Application Notes

The stated application concentrations are suggested starting points. Titration of the LXN antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 78-107 from the human protein was used as the immunogen for the LXN antibody.

Storage

Aliquot the LXN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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