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Home >> Antibodies >> LLGL2 Antibody / HGL

LLGL2 Antibody / HGL (F53918)

  Catalog No Formulation Size Price (USD)  
Image F53918-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 439
Image
F53918-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 205
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Western blot testing of LLGL2 antibody and 293 cell lysate. Predicted molecular weight ~113 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity SAS precipitation followed by dialysis in PBS
UniProt Q6P1M3
Applications Western Blot : 1:500-1000
Limitations This LLGL2 antibody is available for research use only.
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Description

The lethal (2) giant larvae protein of Drosophila / Human giant larvae homolog plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Application Notes

Titration of the LLGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 165-199 from the human protein was used as the immunogen for the LLGL2 antibody.

Storage

Aliquot the LLGL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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