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Home >> Antibodies >> LLGL2 Antibody / HGL

LLGL2 Antibody / HGL (F53918)

  Catalog No Formulation Size Price (USD)  
Image F53918-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F53918-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot testing of LLGL2 antibody and 293 cell lysate. Predicted molecular weight ~113 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity SAS precipitation followed by dialysis in PBS
UniProt Q6P1M3
Applications Western blot : 1:500-1000
Limitations This LLGL2 antibody is available for research use only.
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    Reactivity : Human

Description

The lethal (2) giant larvae protein of Drosophila / Human giant larvae homolog plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Application Notes

Titration of the LLGL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 165-199 from the human protein was used as the immunogen for the LLGL2 antibody.

Storage

Aliquot the LLGL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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