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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways.
Variations in secondary/substrate sensitivities and test protocols may require the LKB1 antibody to be titrated for optimal performance.
Human partial recombinant protein (AA 62-430) was used as the immunogen for this LKB1 antibody.
The lyophilized LKB1 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freeze/thaws.
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