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Home >> Antibodies >> Liver Carboxylesterase 1 Antibody / CES1

Liver Carboxylesterase 1 Antibody / CES1 (RQ6606)

  Catalog No Formulation Size Price (USD)  
Image RQ6606 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human HepG2 cell lysate with Liver Carboxylesterase 1 antibody. Predicted molecular weight ~63 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P23141
Applications Western blot : 1-2ug/ml
Limitations This Liver Carboxylesterase 1 antibody is available for research use only.
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Description

Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene. This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Application Notes

Optimal dilution of the Liver Carboxylesterase 1 antibody should be determined by the researcher.

Immunogen

Amino acids TNLFAKKAVEKPPQTEHIEL from the human protein were used as the immunogen for the Liver Carboxylesterase 1 antibody.

Storage

After reconstitution, the Liver Carboxylesterase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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