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Home >> Antibodies >> LGALS3 Antibody / Galectin 3

LGALS3 Antibody / Galectin 3 [clone LGALS3/4792] (V9668)

  Catalog No Formulation Size Price (USD)  
Image V9668-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V9668-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V9668SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human thyroid carcinoma with LGALS3 antibody (clone LGALS3/4792). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human thyroid carcinoma tissue with LGALS3 antibody (clone LGALS3/4792). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free LGALS3 antibody (clone LGALS3/4792) as confirmation of integrity and purity.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using LGALS3 antibody (clone LGALS3/4792). These results demonstrate the foremost specificity of the LGALS3/4792 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name LGALS3/4792
Purity Protein A/G affinity
UniProt P17931
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This LGALS3 antibody is available for research use only.
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Description

Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

Application Notes

Optimal dilution of the LGALS3 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 150-200 from the human protein was used as the immunogen for the LGALS3 antibody.

Storage

Aliquot the LGALS3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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