- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
LEF1 Antibody [clone 661CT8.3.5] (F53737)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F53737-0.1ML | In ascites with 0.09% sodium azide | 0.1 ml | 399 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Format | Ascites |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Clone Name | 661CT8.3.5 |
| Purity | Ascites |
| UniProt | Q9UJU2 |
| Applications | Western blot : 1:500-1:8000 |
| Limitations | This LEF1 antibody is available for research use only. |
|
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This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Titration of the LEF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 10-37 from the human protein was used as the immunogen for this LEF1 antibody.
Aliquot the LEF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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