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Home >> Antibodies >> LBP Antibody

LBP Antibody (R32868)

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  Catalog No Formulation Size Price (USD)  
Image R32868 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human HeLa, 2) human Jurkat, 3) human A549, 4) human Raji, 5) rat liver and 6) mouse liver lysate with LBP antibody at 0.5ug/ml. Predicted molecular weight ~53 kDa (unmodified), 60-65 kDa (glycosylated).
Western blot testing of 1) human HeLa, 2) human Jurkat, 3) human A549, 4) human Raji, 5) rat liver and 6) mouse liver lysate with LBP antibody at 0.5ug/ml. Predicted molecular weight ~53 kDa (unmodified), 60-65 kDa (glycosylated).
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt Q61805
Applications Western Blot : 0.5-1ug/ml
ELISA (Capture-recombinant mouse protein) : 0.1-0.5ug/ml (BSA-free format available)
Limitations This LBP antibody is available for research use only.
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Description

Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

Application Notes

Optimal dilution of the LBP antibody should be determined by the researcher.

Immunogen

A recombinant mouse protein corresponding to amino acids V26-R257 was used as the immunogen for the LBP antibody.

Storage

After reconstitution, the LBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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