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Home >> Antibodies >> Lambda Light Chain Antibody

Lambda Light Chain Antibody [clone LLC/1738] (V3262)

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  Catalog No Formulation Size Price (USD)  
Image V3262-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3262-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3262SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC testing of FFPE human tonsil stained with Lambda Light Chain antibody (clone LLC/1738). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
IHC testing of FFPE human tonsil stained with Lambda Light Chain antibody (clone LLC/1738). Required HIER: boil tissue sections in 10mM citrate buffer, pH 6, for 10-20 min.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name LLC/1738
Purity Protein G affinity chromatography
UniProt P01701 , P01842
Localization Cell Surface, Cytoplasmic and Secreted
Applications Immunohistochemistry (FFPE) : 0.1-0.2ug/ml for 30 min at RT
Limitations This Lambda Light Chain antibody is available for research use only.
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Description

This mAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with kappa light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Application Notes

The optimal dilution of the Lambda Light Chain antibody for each application should be determined by the researcher.

Immunogen

Purified human lambda light chain was used as the immunogen for this Lambda Light Chain antibody.

Storage

Store the Lambda Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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