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Home >> Antibodies >> Kv1.1 Antibody / KCNA1

Kv1.1 Antibody / KCNA1 (R31420)

  Catalog No Formulation Size Price (USD)  
Image R31420 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Kv1.1 antibody and Lane 1: rat brain; 2: (r) testis; 3: (r) heart; 4: human HeLa; 5: (h) U87; 6: (h) SHG-44; 7: mouse Neuro-2a lysate. Expected molecular weight: 56-85 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q09470
Applications Western blot : 0.5-1ug/ml
Limitations This Kv1.1 antibody is available for research use only.
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Description

Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Kv1.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human Kv1.1 (IAHYRQVNIRTANCTTA) was used as the immunogen for this Kv1.1 antibody.

Storage

After reconstitution, the Kv1.1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Cross
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