Ku70 Antibody / DNA End Binding Protein Antibody (R31952)

Ku70 Antibody Pancreatic Ductal Adenocarcinoma IHC. Immunohistochemistry analysis of FFPE human pancreatic ductal adenocarcinoma tissue stained with Ku70 Antibody demonstrates strong predominantly nuclear HRP-DAB brown staining throughout malignant gland-forming epithelial tumor cell populations, consistent with XRCC6 / Ku70-associated DNA damage response pathway expression. This DNA end binding protein antibody highlights non-homologous end joining-associated repair signaling and genomic stability regulation within pancreatic carcinoma tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Testicular Seminoma IHC. Immunohistochemistry analysis of FFPE human testicular seminoma tissue stained with Ku70 Antibody demonstrates strong diffuse nuclear HRP-DAB brown staining throughout neoplastic germ cell-associated tumor populations, consistent with XRCC6 / Ku70-associated DNA damage response pathway expression. This DNA end binding protein antibody highlights non-homologous end joining-associated repair signaling and genomic stability regulation within seminoma tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Colon Adenocarcinoma IHC. Immunohistochemistry analysis of FFPE human colon adenocarcinoma tissue stained with Ku70 Antibody demonstrates strong predominantly nuclear HRP-DAB brown staining throughout gland-forming malignant epithelial tumor cell populations, consistent with XRCC6 / Ku70-associated DNA repair pathway expression. This DNA end binding protein antibody highlights double-strand break repair signaling and genomic maintenance-associated cellular regulation within colorectal carcinoma tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Colon Adenocarcinoma IHC. Immunohistochemistry analysis of FFPE human colon adenocarcinoma tissue stained with Ku70 Antibody demonstrates strong predominantly nuclear HRP-DAB brown staining throughout gland-forming malignant epithelial tumor cell populations, consistent with XRCC6 / Ku70-associated DNA repair pathway expression. This DNA end binding protein antibody highlights double-strand break repair signaling and genomic maintenance-associated cellular regulation within colorectal carcinoma tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Liver Cancer IHC. Immunohistochemistry analysis of FFPE human liver cancer tissue stained with Ku70 Antibody demonstrates strong diffuse nuclear HRP-DAB brown staining throughout malignant hepatic tumor cell populations, consistent with XRCC6 / Ku70-associated DNA damage response pathway expression. This DNA end binding protein antibody highlights non-homologous end joining-associated repair signaling and genomic stability regulation within hepatocellular carcinoma-associated tissue compartments. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Glioblastoma IHC. Immunohistochemistry analysis of FFPE human glioblastoma tissue stained with Ku70 Antibody demonstrates widespread nuclear HRP-DAB brown staining throughout densely cellular malignant glial-associated tumor populations, consistent with XRCC6 / Ku70-associated DNA repair pathway expression. This DNA end binding protein antibody highlights double-strand break repair signaling and genomic maintenance-associated cellular regulation within high-grade glioma tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Bladder Cancer IHC. Immunohistochemistry analysis of FFPE human bladder cancer tissue stained with Ku70 Antibody demonstrates strong predominantly nuclear HRP-DAB brown staining throughout malignant urothelial-associated tumor cell populations, consistent with XRCC6 / Ku70-associated DNA damage response pathway expression. This DNA end binding protein antibody highlights non-homologous end joining-associated repair signaling and genomic stability regulation within bladder carcinoma tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

Ku70 Antibody Colon Cancer Immunofluorescence. Immunofluorescent analysis of FFPE human colon cancer tissue stained with Ku70 Antibody demonstrates strong nuclear and chromatin-associated red fluorescence throughout malignant gland-forming epithelial tumor cell populations, consistent with XRCC6 / Ku70-associated DNA damage response pathway localization. This DNA end binding protein antibody highlights non-homologous end joining-associated repair signaling and genomic stability regulation within colorectal carcinoma tissue. Nuclei are counterstained with DAPI nuclear stain (blue). HIER: steam section in pH8 EDTA buffer for 20 min.

Ku70 Antibody U-2 OS Immunofluorescence. Immunofluorescent analysis of human U-2 OS cells stained with Ku70 Antibody demonstrates prominent nuclear-associated red fluorescence consistent with XRCC6 / Ku70 localization within DNA damage response and chromatin-associated repair compartments. Co-staining with Beta Tubulin mAb (green) highlights cytoskeletal architecture surrounding Ku70-positive nuclei. This DNA end binding protein antibody supports visualization of non-homologous end joining-associated repair signaling and genomic maintenance pathways in osteosarcoma-derived cells. HIER: steam section in pH6 citrate buffer for 20 min.

Ku70 Antibody Multi-Cell Line WB. Western blot analysis of human 1) LNCaP, 2) HeLa, 3) 293T, 4) HepG2, 5) Jurkat, 6) K562, 7) A549, and 8) A431 cell lysates using Ku70 Antibody detects a strong band at approximately 70 kDa across multiple epithelial and hematopoietic-derived cell lines, consistent with the predicted molecular weight of XRCC6 / Ku70. This DNA end binding protein antibody highlights broad expression of non-homologous end joining-associated DNA repair machinery and genomic stability pathways in diverse human cellular populations.

Ku70 Antibody A431 FACS. Flow cytometry analysis of fixed and permeabilized human A431 cells stained with Ku70 Antibody demonstrates a pronounced right-shifted fluorescence population relative to the isotype control, consistent with intracellular XRCC6 / Ku70 expression associated with DNA damage response and double-strand break repair pathways. This DNA end binding protein antibody supports characterization of non-homologous end joining-associated genomic maintenance signaling in epithelial-derived tumor cells. Red=cells alone, Green=isotype control, Blue=Ku70 antibody.