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Home >> Antibodies >> KRT5 Antibody / Cytokeratin 5 / C-terminal region

KRT5 Antibody / Cytokeratin 5 / C-terminal region [clone AGD-11] (RQ5410)

  Catalog No Formulation Size Price (USD)  
Image RQ5410 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 439
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IHC staining of FFPE human urothelial carcinoma with KRT5 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Western blot testing of human A431 cell lysate with KRT5 antibody. Predicted molecular weight: 58-62 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AGD-11
Purity Affinity purified
UniProt P13647
Localization Cytoplasmic
Applications Western Blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This KRT5 antibody is available for research use only.
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Description

The protein encoded by the KRT5 gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [RefSeq]

Application Notes

Optimal dilution of the KRT5 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to the C-terminal region of human Cytokeratin 5 / KRT5 was used as the immunogen for the KRT5 antibody.

Storage

Store the KRT5 antibody at -20oC.

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