- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
KNG1 Antibody / Kininogen 1 / Bradykinin (F54608)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54608-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54608-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | P01042 |
| Localization | Cytoplasmic |
| Applications | Western blot : 1:500-1:2000 Flow cytometry : 1:25 (1x10e6 cells) Immunohistochemistry (FFPE) : 1:25 |
| Limitations | This KNG1 antibody is available for research use only. |
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This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
The stated application concentrations are suggested starting points. Titration of the KNG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 138-166 from the human protein was used as the immunogen for the KNG1 antibody.
Aliquot the KNG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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