KLK7 Antibody - Protein Microarray Validated [clone KLK7/4691] (V4649)

KLK7 Antibody - Protein Microarray Validated clone KLK7/4691 specificity analysis of Kallikrein 7 / KLK7 using a HuProt(TM) protein array. Analysis of a HuProt(TM) microarray containing more than 19,000 full-length human proteins was performed with KLK7 Antibody - Protein Microarray Validated (clone KLK7/4691). The antibody shows strong and selective binding to KLK7, demonstrating high specificity across the human proteome. Z-score represents the strength of signal generated when the monoclonal antibody, together with a fluorescently labeled anti-IgG secondary antibody, binds to a specific protein on the HuProt(TM) array. Z-scores are expressed in units of standard deviations above the mean signal across the array. When proteins are ranked by Z-score, the S-score represents the difference between consecutive Z-scores and reflects relative antibody specificity for the intended target. Antibodies with an S-score greater than 2.5 are considered highly specific, supporting selective recognition of KLK7 by clone KLK7/4691.

KLK7 Antibody - Protein Microarray Validated clone KLK7/4691 immunohistochemistry analysis of Kallikrein 7 / KLK7 in human skin tissue. FFPE human skin tissue was stained with KLK7 Antibody - Protein Microarray Validated (clone KLK7/4691) following heat induced epitope retrieval by boiling tissue sections in pH 9 Tris-EDTA buffer (10mM Tris, 1mM EDTA) for 20 minutes prior to cooling and staining. HRP-DAB brown chromogenic signal highlights strong staining along the outer epidermal layers of keratinocytes near the stratum corneum, consistent with the known localization of Kallikrein 7 (KLK7), also known as stratum corneum chymotryptic enzyme, in differentiated epidermal cells involved in skin barrier turnover and desquamation. Detection of KLK7 expression by immunohistochemistry supports studies of epidermal differentiation, keratinocyte biology, and dermatological disease research.