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- Email: info@nsjbio.com
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Optimal dilution of the KLF12 antibody should be determined by the researcher.
Recombinant full-length human protein was used as the immunogen for the KLF12 antibody.
Aliquot the KLF12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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