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Home >> Antibodies >> Kindlin-3 Antibody / FERMT3

Kindlin-3 Antibody / FERMT3 (F53966)

  Catalog No Formulation Size Price (USD)  
Image F53966-0.2ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.2 ml 399
Image
F53966-0.05ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.05 ml 185
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Western blot testing of mouse spleen lysate with Kindlin-3 antibody at 1:2000. Predicted molecular weight: 76 kDa.
Availability 1-3 business days
Species Reactivity Mouse
Predicted Reactivity Bovine, Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q86UX7
Applications Western blot : 1:1000-2000
Limitations This Kindlin-3 antibody is available for research use only.
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Description

Fermitin family homolog 3, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).

Application Notes

Titration of the Kindlin-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 117-151 from the mouse protein was used as the immunogen for the Kindlin-3 antibody.

Storage

Aliquot the Kindlin-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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