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Home >> Antibodies >> Keratin 18 Antibody / Cytokeratin 18

Keratin 18 Antibody / Cytokeratin 18 [clone KRT18/7056R] (V4283)

  Catalog No Formulation Size Price (USD)  
Image V4283-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4283-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4283SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human prostate tissue with Keratin 18 antibody (clone KRT18/7056R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Keratin 18 antibody (clone KRT18/7056R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name KRT18/7056R
Purity Protein A/G affinity
UniProt P05783
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Keratin 18 antibody is available for research use only.
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Description

This mAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Application Notes

Optimal dilution of the Keratin 18 antibody should be determined by the researcher.

Immunogen

Recombinant human full-length protein was used as the immunogen for the Keratin 18 antibody.

Storage

Aliquot the Keratin 18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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