- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
KEAP1 Antibody [clone 297CT6.1.6] (F40314)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F40314-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F40314-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Human |
| Predicted Reactivity | Pig |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgM, k |
| Clone Name | 297CT6.1.6 |
| Purity | Purified |
| UniProt | Q14145 |
| Applications | Western blot : 1:100 |
| Limitations | This KEAP1 antibody is available for research use only. |
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This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Titration of the KEAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 422-449 from the human protein was used as the immunogen for this KEAP1 antibody.
Aliquot the KEAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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