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- Email: info@nsjbio.com
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Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Titration of the Kdm6b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This Kdm6b antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1023-1057 amino acids from mouse Kdm6b.
Aliquot the Kdm6b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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