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Home >> Antibodies >> KCNH2 Antibody / ERG-1

KCNH2 Antibody / ERG-1 (RQ6647)

  Catalog No Formulation Size Price (USD)  
Image RQ6647 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat brain and 2) mouse brain tissue lysate with KCNH2 antibody. Expected molecular weight: 127-155 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt Q12809
Applications Western blot : 1-2ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This KCNH2 antibody is available for research use only.
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Description

KCNH2, also known as HERG or KV11.1, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel. It is mapped to 7q36.1. KCNH2 forms the major portion of one of the ion channel proteins (the 'rapid' delayed rectifier current (IKr)) that conducts potassium (K+) ions out of the muscle cells of the heart (cardiac myocytes), and this current is critical in correctly timing the return to the resting state (repolarization) of the cell membrane during the cardiac action potential.

Application Notes

Optimal dilution of the KCNH2 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids N128-L1142) was used as the immunogen for the KCNH2 antibody.

Storage

After reconstitution, the KCNH2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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