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Home >> Antibodies >> JAK2 Antibody

JAK2 Antibody (F52643)

  Catalog No Formulation Size Price (USD)  
Image F52643-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52643-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot analysis of lysate from LNCaP cell line using JAK2 antibody diluted at 1:1000. Predicted molecular weight ~130 kDa
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat, Pig, Chicken
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt O60674
Applications Western blot : 1:500
Limitations This JAK2 antibody is available for research use only.
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Description

JAK2 is a non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. [UniProt]

Application Notes

Titration of the JAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This JAK2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 834-868 amino acids from the C-terminal region of human JAK2.

Storage

Aliquot the JAK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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