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Home >> Antibodies >> ITGAV Antibody / Integrin alpha V

ITGAV Antibody / Integrin alpha V (RQ5735)

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  Catalog No Formulation Size Price (USD)  
Image RQ5735 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of human Raji cells with ITGAV antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= ITGAV antibody.
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Flow cytometry testing of human Raji cells with ITGAV antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= ITGAV antibody.
Western blot testing of human 1) A549 and 2) A431 cell lysate with ITGAV antibody. Expected molecular weight: 116-150 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P06756
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This ITGAV antibody is available for research use only.
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Description

Integrin alpha-V is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene(VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.

Application Notes

Optimal dilution of the ITGAV antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids H732-D970) was used as the immunogen for the ITGAV antibody.

Storage

After reconstitution, the ITGAV antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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