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Home >> Antibodies >> ITGA4 Antibody / Integrin alpha 4

ITGA4 Antibody / Integrin alpha 4 [clone IHH-9] (RQ5406)

  Catalog No Formulation Size Price (USD)  
Image RQ5406 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing of human Jurkat cell lysate with ITGA4 antibody. Predicted molecular weight ~115 kDa, routinely observed at ~150 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name IHH-9
Purity Affinity purified
UniProt P13612
Applications Western blot : 1:500-1:2000
Limitations This ITGA4 antibody is available for research use only.
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Description

The ITGA4 gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [RefSeq]

Application Notes

Optimal dilution of the ITGA4 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Integrin alpha 4 / ITGA4 was used as the immunogen for the ITGA4 antibody.

Storage

Store the ITGA4 antibody at -20oC.

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