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Home >> Antibodies >> IRF8 Antibody

IRF8 Antibody (F48244)

  Catalog No Formulation Size Price (USD)  
Image F48244-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48244-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IRF8 antibody flow cytometric analysis of HL-60 cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Western blot analysis of IRF8 antibody and HL-60 lysate. Predicted molecular weight ~48kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q02556
Applications Western blot : 1:1000
Flow Cytometry : 1:10-1:50
Limitations This IRF8 antibody is available for research use only.
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Description

Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Application Notes

Titration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 384-409 from the human protein was used as the immunogen for this IRF8 antibody.

Storage

Aliquot the IRF8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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