- Tel: 858.663.9055
- Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Titration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 384-409 from the human protein was used as the immunogen for this IRF8 antibody.
Aliquot the IRF8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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