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Home >> Antibodies >> IRF3 Antibody / Interferon regulatory factor 3

IRF3 Antibody / Interferon regulatory factor 3 [clone PCRP-IRF3-1E6] (V9200)

  Catalog No Formulation Size Price (USD)  
Image V9200-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V9200-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V9200SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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FACS staining of PFA-fixed human HeLa cells with IRF3 antibody (blue, clone PCRP-IRF3-1E6), and isotype control (red).
Immunofluorescent staining of PFA-fixed human HeLa cells using IRF3 antibody (green, clone PCRP-IRF3-1E6) and phalloidin (red).
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using IRF3 antibody (clone PCRP-IRF3-1E6). These results demonstrate the foremost specificity of the PCRP-IRF3-1E6 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free IRF3 antibody (PCRP-IRF3-1E6) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a
Clone Name PCRP-IRF3-1E6
Purity Protein A/G affinity
UniProt Q14653
Localization Cytoplasm, Nucleus
Applications Flow cytometry : 1-2ug/million cells
Immunofluorescence : 1-2ug/ml
Western blot : 1-2ug/ml
Limitations This IRF3 antibody is available for research use only.
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Description

Interferon regulatory factor 3 acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. [UniProt]

Application Notes

Optimal dilution of the IRF3 antibody should be determined by the researcher.

Immunogen

Recombinant full-length human IRF3 protein was used as the immunogen for the IRF3 antibody.

Storage

Aliquot the IRF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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