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Home >> Antibodies >> IRAKM Antibody

IRAKM Antibody (R31330)

  Catalog No Formulation Size Price (USD)  
Image R31330 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of IRAKM antibody and Lane 1: HeLa; 2: Jurkat; 3: HUT102 cell lysate. Predicted molecular weight: ~68kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q9Y616
Applications Western blot : 0.5-1ug/ml
Limitations This IRAKM antibody is available for research use only.
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Description

Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.

Application Notes

The stated application concentrations are suggested starting points. Titration of the IRAKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human IRAKM (WFPKYIVPSQDLRPYKVNID) was used as the immunogen for this IRAKM antibody.

Storage

After reconstitution, the IRAKM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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