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Home >> Antibodies >> IRAK-M Antibody

IRAK-M Antibody (R31331)

  Catalog No Formulation Size Price (USD)  
Image R31331 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 329
Western blot testing of IRAK-M antibody and Lane 1: HeLa; 2: Jurkat cell lysate. Predicted molecular weight: ~68kDa.
IHC-P: IRAK-M antibody testing of human lung cancer tissue
IHC-P: IRAK-M antibody testing of mouse liver tissue
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt Q8K4B2
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Immunocytochemistry : 0.1-0.5ug/ml
Limitations This IRAK-M antibody is available for research use only.
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Description

IL1 receptor associated kinase M (IRAK-M), or Interleukin-1 receptor-associated kinase 3, is an enzyme that in humans is encoded by the IRAK3 gene and a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the TLR/ILR immune signal transduction pathways. IRAK-M functions as a negative regulator of Toll-like receptor signaling.

Application Notes

Titration of the IRAK-M antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids KHLWYMPEEYIRQGRL (mouse 349-364) were used as the immunogen for this IRAK-M antibody (100% rat homology).

Storage

After reconstitution, the IRAK-M antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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