- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Interleukin-1 Receptor Antagonist Antibody / IL1RA / IL1RN [clone 12C13] (RQ6530)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ6530 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
|
| Availability | 1-3 business days |
| Species Reactivity | Rat |
| Format | Antigen affinity purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2b |
| Clone Name | 12C13 |
| Purity | Affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | P25086 |
| Applications | ELISA (Capture) : 1-5ug/ml |
| Limitations | This Interleukin-1 Receptor Antagonist antibody is available for research use only. |
|
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The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
For a monoclonal clone with protein microarray specificity validation, see our IL1RN Antibody IL1RA/4716 / Interleukin-1 Receptor Antagonist Antibody page.
Optimal dilution of the Interleukin-1 Receptor Antagonist antibody should be determined by the researcher.
An E. coli-derived rat protein (amino acids H27-Q178) was used as the immunogen for the Interleukin-1 Receptor Antagonist antibody.
After reconstitution, the Interleukin-1 Receptor Antagonist antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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