Interferon Regulatory Factor 3 Antibody / Antiviral Response Protein Antibody [clone PCRP-IRF3-4D7] (V4643)

Interferon Regulatory Factor 3 Antibody HeLa FACS. Flow cytometry analysis of PFA-fixed human HeLa cells stained with Interferon Regulatory Factor 3 Antibody demonstrates a distinct right-shifted fluorescence population relative to unstained cells, consistent with IRF3-associated antiviral signaling and interferon regulatory pathway expression. This antiviral response protein antibody supports characterization of innate immune-associated transcriptional regulatory proteins in epithelial-derived cells. Blue=IRF3 antibody, Red=unstained cells.

Interferon Regulatory Factor 3 Antibody Tumor IHC. Immunohistochemistry analysis of FFPE human tumor tissue stained with Interferon Regulatory Factor 3 Antibody demonstrates predominantly nuclear HRP-DAB brown staining within malignant epithelial cell populations, consistent with activated IRF3-associated antiviral signaling and interferon-regulatory transcriptional pathway activity. This antiviral response protein antibody highlights innate immune-associated transcriptional regulation and stress-response signaling within tumor tissue. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free Interferon regulatory factor 3 antibody (clone PCRP-IRF3-4D7) as confirmation of integrity and purity.

Interferon Regulatory Factor 3 Antibody HuProt Microarray Validation. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Interferon Regulatory Factor 3 Antibody demonstrates highly selective recognition of IRF3 with strong separation from non-target proteins across the tested human proteome. These results support the high specificity of the PCRP-IRF3-4D7 mAb for interferon regulatory factor 3-associated antiviral signaling pathways and innate immune regulatory proteins. The Z-score represents the strength of antibody binding signal relative to the overall array mean, while the S-score reflects target specificity relative to the next highest ranked protein signal. The elevated S-score separation observed for IRF3 supports preferential target recognition across the tested human proteome.