- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Interferon Induced Transmembrane Protein 1 Antibody / IFITM1 Antibody (RQ7018)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
RQ7018 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | P13164 |
| Applications | Western Blot : 0.5-1 ug/ml Direct ELISA : 0.1-0.5ug/ml |
| Limitations | This Interferon Induced Transmembrane Protein 1 Antibody / IFITM1 Antibody is available for research use only. |
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Interferon Induced Transmembrane Protein 1 Antibody / IFITM1 Antibody recognizes IFITM1, an interferon-responsive membrane protein that is rapidly induced following activation of innate immune signaling pathways. The full protein name, Interferon Induced Transmembrane Protein 1, emphasizes its regulation by interferons and its localization within cellular membranes, two characteristics that define its biological function. IFITM1 is best known for limiting viral entry by altering membrane properties and reducing membrane fusion events required for infection. Because of its central role in host defense, an Interferon Induced Transmembrane Protein 1 Antibody is widely used to investigate antiviral immunity, interferon-mediated signaling, and cellular responses to inflammatory cytokines.
Interferon Induced Transmembrane Protein 1 is expressed in numerous epithelial, endothelial, and hematopoietic cell populations, with expression increasing dramatically after stimulation with type I and type II interferons. The protein localizes primarily to the plasma membrane and intracellular membrane compartments, where it participates in regulating membrane organization, vesicular trafficking, and receptor-associated signaling. Although initially characterized as an antiviral restriction factor, IFITM1 has since been shown to influence cell adhesion, migration, proliferation, and immune cell communication. Researchers frequently evaluate Interferon Induced Transmembrane Protein 1 together with IFITM2, IFITM3, interferon-stimulated genes, and additional immune biomarkers to better understand host defense mechanisms and cytokine-driven cellular responses. A Interferon Induced Transmembrane Protein 1 Antibody therefore provides valuable insight into interferon biology and membrane-associated immune regulation.
Abnormal expression of Interferon Induced Transmembrane Protein 1 has been reported in a wide variety of malignancies, including colorectal, gastric, breast, lung, cervical, and head and neck cancers. Elevated expression has been associated with increased tumor growth, migration, invasion, epithelial-to-mesenchymal transition, immune evasion, and resistance to therapeutic intervention. Beyond oncology, dysregulated IFITM1 expression has been investigated in viral infections, chronic inflammatory diseases, and autoimmune disorders in which persistent interferon signaling contributes to disease progression. Consequently, an Interferon Induced Transmembrane Protein 1 Antibody has become an important research reagent for studies examining immune activation, inflammatory signaling, host-pathogen interactions, and cancer biology.
Interferon Induced Transmembrane Protein 1 is routinely analyzed using Western blot, immunohistochemistry, immunofluorescence, flow cytometry, and immunoprecipitation to evaluate protein expression, membrane localization, and regulation during immune activation or disease progression. Its inducible expression pattern makes it an informative biomarker for monitoring interferon responses and innate immune activity across diverse experimental models. NSJ Bioreagents provides carefully validated antibodies to support these applications in immunology, oncology, virology, and cell biology research. An Interferon Induced Transmembrane Protein 1 Antibody provides researchers with a dependable tool for investigating IFITM1 biology, antiviral defense, membrane protein function, and interferon-regulated cellular processes.
Visit our IFITM1 Antibody / Interferon Induced Transmembrane Protein Antibody page for additional information about validated antibodies for investigating IFITM1 expression, interferon signaling, innate immunity, antiviral defense, and membrane-associated cellular responses.
Optimal dilution of the Interferon Induced Transmembrane Protein 1 Antibody / IFITM1 Antibody should be determined by the researcher.
Recombinant human protein (amino acids M1-Y125) was used as the immunogen for the Interferon Induced Transmembrane Protein 1 antibody.
After reconstitution, the Interferon Induced Transmembrane Protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Interferon Induced Transmembrane Protein 1 antibody, IFITM1 antibody, CD225 antibody, Interferon Induced Transmembrane Protein antibody
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