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Home >> Antibodies >> Interferon gamma Antibody

Interferon gamma Antibody [clone 8E9.] (RQ4510)

  Catalog No Formulation Size Price (USD)  
Image RQ4510 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Availability 1-3 business days
Species Reactivity Rat
Format Purified
Clonality Monoclonal
Isotype Mouse IgG1
Clone Name 8E9.
Purity Protein G affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P01581
Localization Secreted
Applications Capture ELISA : 1-5ug/ml (rat recombinant protein)
Limitations This Interferon gamma antibody is available for research use only.
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Description

Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

Application Notes

Optimal dilution of the Interferon gamma antibody should be determined by the researcher.

Immunogen

Rat Interferon gamma recombinant protein (amino acids Q23-C156) was used as the immunogen for the Interferon gamma antibody.

Storage

After reconstitution, the Interferon gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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