- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Interferon gamma Antibody (R30566)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R30566 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | P01579 |
| Localization | Cytoplasmic, membranous, extracellular (secreted) |
| Applications | Western blot : 0.5-1ug/ml |
| Limitations | This Interferon gamma antibody is available for research use only. |
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Interferon gamma is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFNg, which is under genetic control, can influence the development of fibrosis in lung allografts. It is also produced by natural killer(NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFNg and expression might be important for the development of tuberculosis. It activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, Interferon gamma has important immunoregulatory functions and plays an important role in the control of neointima proliferation.
The stated application concentrations are suggested starting amounts. Titration of the Interferon gamma antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human IFNg (KRKRSQMLFRGRRASQ) was used as the immunogen for this Interferon gamma antibody.
After reconstitution, the Interferon gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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