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Home >> Antibodies >> Interferon gamma Antibody

Interferon gamma Antibody [clone 8E9.] (RQ4510)

  Catalog No Formulation Size Price (USD)  
Image RQ4510 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 449
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Availability 1-3 business days
Species Reactivity Rat
Format Purified
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG1
Clone Name 8E9.
Purity Protein G affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P01581
Localization Secreted
Applications Capture ELISA : 1-5ug/ml (rat recombinant protein)
Limitations This Interferon gamma antibody is available for research use only.
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Description

Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

For an alternative recombinant monoclonal clone targeting IFNG, see our Interferon gamma Antibody rIFNG/4467 / Type II Interferon Antibody page.

Application Notes

Optimal dilution of the Interferon gamma antibody should be determined by the researcher.

Immunogen

Rat Interferon gamma recombinant protein (amino acids Q23-C156) was used as the immunogen for the Interferon gamma antibody.

Storage

After reconstitution, the Interferon gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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