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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.
For an alternative recombinant monoclonal clone targeting IFNG, see our Interferon gamma Antibody rIFNG/4467 / Type II Interferon Antibody page.
Optimal dilution of the Interferon gamma antibody should be determined by the researcher.
Rat Interferon gamma recombinant protein (amino acids Q23-C156) was used as the immunogen for the Interferon gamma antibody.
After reconstitution, the Interferon gamma antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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