- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Interferon Alpha-1 Antibody 2-52 / IFNA1 Protein Antibody [clone 2-52] (V2611)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
V2611-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 559 | |
|
|
V2611-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 259 | |
|
|
V2611SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 559 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Host | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | 2-52 |
| Purity | Protein G affinity chromatography |
| UniProt | P01562 |
| Localization | Cytoplasmic, extracellular (secreted) |
| Applications | ELISA (order The BSA-free Format For Coating) : |
| Limitations | This Interferon Alpha-1 Antibody 2-52 / IFNA1 Protein Antibody is available for research use only. |
|
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Interferon Alpha-1 Antibody 2-52 / IFNA1 Protein Antibody recognizes interferon alpha 1 (IFNA1), a member of the type I interferon family involved in antiviral defense and immune regulation. IFNA1 signals through the heterodimeric type I interferon receptor composed of IFNAR1 and IFNAR2. Receptor engagement activates JAK-STAT signaling and induces expression of interferon-stimulated genes that contribute to antiviral activity, immune-cell regulation, and cellular responses to infection.
Interferon alpha proteins are produced following viral infection and other immune stimuli and function as important mediators between innate and adaptive immune responses. IFNA1 can influence antiviral defense, antigen presentation, natural killer cell activity, dendritic cell function, and inflammatory signaling. These activities make IFNA1 Protein relevant to investigations of host defense, cytokine signaling, immune regulation, and the interactions between interferon pathways and disease biology.
The human interferon alpha family contains multiple closely related proteins encoded by distinct genes. Their substantial sequence similarity can make differentiation among individual family members challenging, even though interferon alpha subtypes can differ in expression and biological activity. Distinguishing IFNA1 from closely related IFNA2 is therefore useful when investigating subtype-specific interferon biology rather than the broader interferon alpha response.
Clone 2-52 is a mouse monoclonal antibody recognizing human IFNA1 without cross-reactivity to interferon alpha 2. NSJ Bioreagents offers this Interferon Alpha-1 Antibody for researchers investigating IFNA1 expression, cytokine biology, and type I interferon signaling. An Interferon Alpha-1 Antibody provides a clone-defined reagent for studying IFNA1 Protein independently of the closely related IFNA2 subtype.
For an alternative monoclonal clone with documented specificity for IFNA1 without cross-reactivity to IFNA2, see our Interferon Alpha 1 Antibody IFNA/6689 / IFNA1 Antibody page.
Optimal dilution of the Interferon Alpha-1 Antibody 2-52 / IFNA1 Protein Antibody should be determined by the researcher.
Purified recombinant human protein was used as the immunogen for the Interferon Alpha-1 Antibody 2-52.
Store the Interferon Alpha-1 Antibody 2-52 at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
IFNA1 antibody, Interferon alpha 1 antibody, Interferon alpha-1 antibody, IFNA1 protein antibody, IFN alpha 1 antibody, IFN-alpha 1 antibody
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