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Home >> Antibodies >> Integrin beta 2 Antibody

Integrin beta 2 Antibody [clone 534CT6.2.1] (F40395)

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  Catalog No Formulation Size Price (USD)  
Image F40395-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
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F40395-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Immunohistochemical analysis of paraffin-embedded human tonsil using Integrin beta 2 antibody at 1:25 dilution.
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Immunohistochemical analysis of paraffin-embedded human tonsil using Integrin beta 2 antibody at 1:25 dilution.
Integrin beta 2 antibody western blot analysis in K562 lysate. Predicted molecular weight 85~95 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 534CT6.2.1
Purity Purified
UniProt P05107
Applications IHC (Paraffin) : 1:25
Western blot : 1:100-1:1000
Limitations This Integrin beta 2 antibody is available for research use only.
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Description

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

Application Notes

Titration of the Integrin beta 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Purified His-tagged protein fragment was used to produced this monoclonal Integrin beta 2/CD18 antibody.

Storage

Aliquot the Integrin beta 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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