- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Integrin alpha 3 Antibody (F53345)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
F53345-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 439 | |
|
|
F53345-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 205 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P26006 |
| Applications | Western Blot : 1:2000-4000 |
| Limitations | This Integrin alpha 3 antibody is available for research use only. |
|
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Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
For an alternative antibody targeting the same cell adhesion receptor, see our ITGA3 Antibody.
Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This Integrin alpha 3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.
Aliquot the Integrin alpha 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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