- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Insulin Antibody [clone 396CT20.4.4] (F53596)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F53596-0.1ML | In ascites with 0.09% sodium azide | 0.1 ml | 399 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Ascites |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgM |
| Clone Name | 396CT20.4.4 |
| Purity | Ascites |
| UniProt | P01308 |
| Applications | Western blot : 1:1000-1:8000 |
| Limitations | This Insulin antibody is available for research use only. |
|
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After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Titration of the Insulin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 35-64 from the human protein was used as the immunogen for this Insulin antibody.
Aliquot the Insulin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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