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- Tel: 858.663.9055
- Email: info@nsjbio.com
IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
Optimal dilution of the INSM2 antibody should be determined by the researcher.
A portion of amino acids 432-540 from the human protein was used as the immunogen for the INSM2 antibody.
Store the INSM2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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