- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recombinant INS Antibody rIRDN/4782 / Recombinant Insulin Antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
For a highly published insulin monoclonal with an alternate INS05 clone designation, see our Insulin Antibody 2D11-H5 / INS05 Antibody page.
Optimal dilution of the Recombinant INS Antibody rIRDN/4782 / Recombinant Insulin Antibody should be determined by the researcher.
Recombinant full-length human Insulin protein was used as the immunogen for the Recombinant INS Antibody rIRDN/4782.
Aliquot the Recombinant INS Antibody rIRDN/4782 and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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