- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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INF2 Antibody / Actin Regulation Protein Antibody detects Inverted Formin 2, a member of the formin family of proteins involved in actin cytoskeleton remodeling, cellular structure regulation and intracellular organization. INF2 is unique among formin proteins because it can promote both actin filament assembly and actin depolymerization, allowing dynamic control of cytoskeletal architecture. Through its regulation of actin turnover, INF2 contributes to processes including cell morphology, organelle positioning, vesicle movement and cellular response to structural changes. Its specialized role in actin dynamics makes INF2 an important target for studies of cytoskeleton regulation and cell biology.
INF2 contains conserved formin homology domains that regulate actin filament nucleation and elongation. Unlike many other formin proteins that primarily promote actin assembly, INF2 also contains regions that enhance actin filament disassembly, allowing rapid remodeling of actin networks. INF2 activity influences endoplasmic reticulum organization, mitochondrial dynamics, intracellular transport and interactions between organelles and the cytoskeleton. INF2 Antibody is commonly used by researchers investigating actin remodeling pathways, cytoskeletal organization and mechanisms controlling cellular architecture.
Research involving INF2 has expanded into areas including kidney disease, neurological disorders and membrane trafficking biology. Mutations in INF2 have been associated with focal segmental glomerulosclerosis and Charcot-Marie-Tooth disease, highlighting the importance of actin regulation in specialized cell types such as podocytes and neurons. INF2-mediated actin remodeling has also been studied in relation to mitochondrial fission, cellular stress responses and maintenance of intracellular organization. These diverse functions connect INF2 to both fundamental cytoskeleton research and disease-associated cellular pathways.
INF2 Antibody applications include analysis of Inverted Formin 2 expression, localization and regulation in biological research samples using methods such as Western blot, immunohistochemistry, immunofluorescence and flow cytometry. Detection of INF2 helps researchers investigate actin dynamics, cytoskeletal remodeling, organelle regulation and cellular structural control mechanisms. NSJ Bioreagents provides INF2 Antibody / Actin Regulation Protein Antibody for researchers studying actin biology, intracellular organization and cell regulation pathways.
INF2 Antibody detects an actin-regulating formin protein involved in cytoskeletal remodeling, organelle dynamics and cellular structure regulation, making it a useful marker for research areas featured in our Cell Biology Antibodies page.
Optimal dilution of the INF2 Antibody / Actin Regulation Protein Antibody should be determined by the researcher.
E. coli-derived recombinant human protein (amino acids A7-Q674) was used as the immunogen for the INF2 antibody.
After reconstitution, the INF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Inverted Formin 2 Antibody, Inverted Formin-2 Antibody, Formin Protein Antibody, Actin Polymerization Protein Antibody, FSGS5 Antibody, CMTDIE Antibody
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