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Home >> Antibodies >> IL-7 Antibody

IL-7 Antibody (R31954)

  Catalog No Formulation Size Price (USD)  
Image R31954 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 419
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Western blot testing of K562 cell lysate with IL-7 antibody. Expected molecular weight: 19-30 kDa depending on glycosylation level, observed here at ~75 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P13232
Applications Western blot : 0.1-0.5ug/ml
ELISA : 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating
Limitations This IL-7 antibody is available for research use only.
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Description

IL-7, Interleukin 7, is a protein that in humans is encoded by the IL-7 gene. IL-7 a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells but is not produced by lymphocytes. By the combination of approaches, IL-7 is located on 8q12-q13. IL-7 is critical for early T-cell development and homeostasis of naive and memory CD8-positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain is critical for early T-cell development and homeostasis of naive and memory CD8 -positive T cells. It signals through the IL-7 receptor complex, which consists of the IL7R-alpha chain and the common IL2R-gamma chain.

Application Notes

Optimal dilution of the IL-7 antibody should be determined by the researcher.

Immunogen

Amino acids 26-177 of human IL7 were used as the immunogen for the IL-7 antibody.

Storage

After reconstitution, the IL-7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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