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Home >> Antibodies >> IL-17F Antibody / Interleukin 17F

IL-17F Antibody / Interleukin 17F (R32917)

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  Catalog No Formulation Size Price (USD)  
Image R32917 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat PC-12 cell lysate with IL-17F antibody at 0.5ug/ml. Predicted molecular weight: ~15 kDa (unmodified monomer), 15-20 kDa (glycosylated monomer), ~30 kDa (homodimer) and 30~40 kDa (glycosylated homodimer).
Western blot testing of rat PC-12 cell lysate with IL-17F antibody at 0.5ug/ml. Predicted molecular weight: ~15 kDa (unmodified monomer), 15-20 kDa (glycosylated monomer), ~30 kDa (homodimer) and 30~40 kDa (glycosylated homodimer).
Availability 1-3 business days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt Q96PD4
Applications Western Blot : 0.5-1ug/ml
Direct ELISA (recombinant human proteion) : 0.1-0.5ug/ml (BSA-free format available)
Limitations This IL-17F antibody is available for research use only.
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Description

Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.

Application Notes

Optimal dilution of the IL-17F antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids R31-Q163 was used as the immunogen for the IL-17F antibody.

Storage

After reconstitution, the IL-17F antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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