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- Email: info@nsjbio.com
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The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Titration of the IL-17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 61-87 from human IL-17A was used as the immunogen for this IL-17 antibody.
Aliquot the IL-17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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