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Home >> Antibodies >> IKK Antibody (alpha/beta)

IKK Antibody (alpha/beta) (F47192)

  Catalog No Formulation Size Price (USD)  
Image F47192-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F47192-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IKK antibody western blot analysis in A549 lysate. Predicted molecular weight ~85 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Bovine
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt O15111
Applications Western blot : 1:1000
Limitations This IKK antibody is available for research use only.
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Description

IKKA is a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

Application Notes

Titration of the IKK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 155-184 from human IKKA was used as the immunogen for this IKK antibody. This sequence is 100% homologous with human IKKB.

Storage

Aliquot the IKK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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