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- Email: info@nsjbio.com
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This antibody recognizes a protein of 75kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Optimal dilution of the IgM Heavy Chain antibody should be determined by the researcher.
Recombinant heavy chain of human IgM was used as the immunogen for this antibody.
Store the IgM Heavy Chain antibody at 2-8oC, protected from light.
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