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Home >> Antibodies >> IgM Heavy Chain Antibody

IgM Heavy Chain Antibody [clone IM373] (V2144CF488)

  Catalog No Formulation Size Price (USD)  
Image V2144CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 499
Availability 1-3 business days
Species Reactivity Human
Format CF488 Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name IM373
Purity Protein G affinity chromatography
Localization Cytoplasm, Cell Surface and Secreted
Applications Flow cytometry : 5ul/test/10^6 cells in 0.1ml
Immunofluorescence : 1-2ug/ml
Limitations This IgM Heavy Chain antibody is available for research use only.
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Description

This antibody recognizes a protein of 75kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Application Notes

Optimal dilution of the IgM Heavy Chain antibody should be determined by the researcher.

Immunogen

Recombinant heavy chain of human IgM was used as the immunogen for this antibody.

Storage

Store the IgM Heavy Chain antibody at 2-8oC, protected from light.

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