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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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IgM Heavy Chain Antibody CF488 Conjugate recognizes a protein of 75kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For detection of total human IgM, see our Human IgM ELISA Antibody RM121 page.
Optimal dilution of the IgM Heavy Chain Antibody CF488 Conjugate should be determined by the researcher.
Recombinant heavy chain of human IgM was used as the immunogen for this IgM Heavy Chain Antibody CF488 Conjugate.
Store the IgM Heavy Chain Antibody CF488 Conjugate at 2-8oC, protected from light.
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