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Home >> Antibodies >> IGFBP3 Antibody

IGFBP3 Antibody (R32836)

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  Catalog No Formulation Size Price (USD)  
Image R32836 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of recombinant human protein with IGFBP3 antibody at 0.5ug/ml. Expected molecular weight: ~31/40-44 kDa (unmodified/glycosylated).
Western blot testing of recombinant human protein with IGFBP3 antibody at 0.5ug/ml. Expected molecular weight: ~31/40-44 kDa (unmodified/glycosylated).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt P17936
Localization Secreted
Applications Western Blot : 0.5-1ug/ml
ELISA (Capture; human recombinant protein) : 0.1-0.5ug/ml (BSA-free formulation available)
Limitations This IGFBP3 antibody is available for research use only.
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Description

IGFBP3, Insulin-like growth fator-binding protein 3, is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 is located on chromosome 7. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Application Notes

Optimal dilution of the IGFBP3 antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids A29-K267 was used as the immunogen for the IGFBP3 antibody.

Storage

After reconstitution, the IGFBP3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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