IGF2BP2 Antibody / RNA Binding Protein Antibody (FY13468)

IGF2BP2 Antibody Human Ovarian Cancer IHC. Immunohistochemical staining of FFPE human ovarian cancer tissue with IGF2BP2 antibody at 2 ug/ml. Heat-induced epitope retrieval (HIER) was performed by boiling tissue sections in pH 8 EDTA buffer prior to staining. IGF2BP2 immunoreactivity is observed predominantly within the cytoplasm of malignant epithelial cells, consistent with the expected localization of this RNA binding protein, which regulates messenger RNA stability, translation, and m6A-dependent post-transcriptional gene expression. Cell nuclei are counterstained with hematoxylin (blue).

IGF2BP2 Antibody A549 Cell IF. Immunofluorescent staining of A549 cells with IGF2BP2 antibody (green) at 5 ug/ml. Enzymatic antigen retrieval was performed for 15 minutes prior to staining. Nuclei are counterstained with DAPI (blue). IGF2BP2 immunoreactivity is observed predominantly within the cytoplasm, consistent with the expected localization of this RNA binding protein, which regulates messenger RNA stability, translation, localization, and m6A-dependent post-transcriptional gene expression.

IGF2BP2 Antibody Human, Rat and Mouse WB. Western blot testing of 1) human Caco-2, 2) human HepG2, 3) human K562, 4) human HEL, 5) rat C6, 6) mouse testis, and 7) mouse NIH/3T3 lysates with IGF2BP2 antibody at 0.5 ug/ml. A distinct immunoreactive band is detected at approximately 66 kDa in all samples, consistent with the predicted molecular weight of IGF2BP2. The results demonstrate specific detection of this RNA binding protein, which regulates messenger RNA stability, localization, translation, and m6A-dependent post-transcriptional gene expression.