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Home >> Antibodies >> IGF-1 Antibody

IGF-1 Antibody [clone IGF1/1020] (V2616)

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  Catalog No Formulation Size Price (USD)  
Image V2616-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2616-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2616SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name IGF1/1020
Purity Protein G affinity chromatography
UniProt P05019
Localization Cytoplasmic (secreted)
Applications Flow cytometry : 0.5-1ug/10^6 cells
Immunofluorescence : 1-4ug/ml
In-vitro neutralization of biological activity of IGF-1 (order BSA/sodium azide-free format) :
Limitations This IGF-1 antibody is available for research use only.
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Description

This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Application Notes

Optimal dilution of the IGF-1 antibody should be determined by the researcher.

Immunogen

Full-length recombinant human IGF1 protein was used as the immunogen for the IGF-1 antibody.

Storage

Store the IGF-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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