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Home >> Antibodies >> IFNA1 Antibody / Interferon alpha 1

IFNA1 Antibody / Interferon alpha 1 [clone 2.48] (V7854)

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  Catalog No Formulation Size Price (USD)  
Image V7854-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7854-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7854SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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SDS-PAGE analysis of purified, BSA-free IFNA1 antibody (clone 2.48) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free IFNA1 antibody (clone 2.48) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name 2.48
Purity Protein G affinity chromatography
UniProt P01562
Localization Cytoplasmic, extracellular (secreted)
Applications Flow cytometry : 1-2ug/10^6 cells in 0.1ml
Western blot : 1-2ug/ml
Immunohistochemistry (frozen) : 1-2ug/ml
Immunofluorescence : 1-2ug/ml
Limitations This IFNA1 antibody is available for research use only.
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Description

This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Application Notes

Optimal dilution of the IFNA1 antibody should be determined by the researcher.

Immunogen

Purified recombinant human protein was used as the immunogen for the Interferon alpha antibody.

Storage

Store the IFNA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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